Cell Fragments: Cell Fragment Formation, Migration, and Force Exertion on Extracellular Mimicking Fiber Nanonets (Adv. Biology 6/2021)
نویسندگان
چکیده
منابع مشابه
Cell Migration through Extracellular Matrix
Every so often, a paper comes along that brings clarity to an issue. Clarity is not necessarily a final resolution, but rather a conceptual framework for productively addressing that issue. Such a paper could be based on a breakthrough discovery, an intriguing observation, a flash of intuition , or a systematic analysis. An excellent example of the latter is in this issue of The Journal of Cell...
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At the onset of collective cell migration, a subset of cells within an initially homogenous population acquires a distinct “leader” phenotype with characteristic morphology and motility. However, the factors driving leader cell formation as well as the mechanisms regulating leader cell density during the migration process remain to be determined. Here, we use single cell gene expression analysi...
متن کاملNotch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration.
At the onset of collective cell migration, a subset of cells within an initially homogenous population acquires a distinct 'leader' phenotype with characteristic morphology and motility. However, the factors driving the leader cell formation as well as the mechanisms regulating leader cell density during the migration process remain to be determined. Here we use single-cell gene expression anal...
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As we know all too well, pancreatic cancer has a very poor prognosis largely due to its early tendency to invade, locally and distantly. Recently, scientists in the field have increasingly focused on the desmoplastic reaction, which is characteristic of most pancreatic cancers. This reaction is associated with proliferation of fibroblastic cells, sometimes outnumbering local tumor cells, and co...
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Objective(s): Circular RNAs (circRNAs), a new class of non-coding RNAs, have emerged as important regulators during tumorigenesis. However, the functions of circRNAs have not been completely clarified in the progression of cancers. In our study, a novel circRNA hsa_circ_0109291 was investigated in oral squamous cell carcinoma (OSCC) tissues and cell lines. Materials and Methods: The expression ...
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ژورنال
عنوان ژورنال: Advanced Biology
سال: 2021
ISSN: 2701-0198,2701-0198
DOI: 10.1002/adbi.202170062